Engineer IV, Process Safety
Company: Takeda
Location: Boston
Posted on: November 14, 2024
Job Description:
By clicking the "Apply" button, I understand that my employment
application process with Takeda will commence and that the
information I provide in my application will be processed in line
with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionAbout the role:At Takeda, we are a
forward-looking, world-class R&D organization that unlocks
innovation and delivers transformative therapies to patients. By
focusing R&D efforts on four therapeutic areas and other
targeted investments, we push the boundaries of what is possible in
order to bring life-changing therapies to patients
worldwide.Synthetic Molecule Process Development (SMPD) is
responsible for the development of robust and cost-effective
processes for the manufacture of new small molecule
pharmaceuticals, along with methods for achieving and controlling
high standards of purity and quality.The successful candidate will
be responsible for the process safety evaluation of chemical
processes by independently planning and executing relevant
experiments. He/She will lead process safety related technology
transfer activities to vendors as well as independently interpret
and communicate process safety results.Additionally, the successful
candidate will be responsible for maintaining SMPD's kilolab
facilities to ensure the safe demonstration of the developed
chemical processes ahead of technical transfer to the manufacturing
organization.How you will contribute:
- Work with process chemists and engineers to perform a thorough
evaluation of all known and potential hazards for the safe scale-up
of chemical processes for preparing pharmaceutical intermediates
and active products in Takeda's research and manufacturing
facilities.
- Prepare complex experimental protocols.
- Collect and integrate relevant process safety data (e.g.,
calorimetry, pressure build-up, off-gassing), using for e.g. DSC,
ARC, TSU, EasyMax, RC-1 and ARC into digital platforms for seamless
data analysis and sharing, ensuring data complies with FAIR
principles (Findable, Accessible, Interoperable, Reusable).
- Work with external vendors to collect relevant process safety
data.
- Summarize and document results in an ELN as well as generate
process safety test reports.
- Conduct a HAZOP analysis and support phase appropriate process
safety testing.
- Partner with internal & external manufacturing organizations to
ensure the safe scale-up of Takeda's processes.
- Draft operating procedures, train SMPD staff and ensure
adherence to quality standards.
- Maintain SMPD's kilolabs, ensuring that they are safe, clean
and functional.
- Manage the kilolab inventory (including chemicals, reagents,
equipment & consumables) and ensure adequate supplies are
available.
- Coordinate with contractors, vendors, and internal stakeholders
to oversee the installation, commissioning, and qualification of
kilolab equipment and systems.
- Oversee internal manufacturing campaigns (e.g. review batch
records, set-up equipment, support execution & cleaning).
- Support local initiatives as directed by his/her supervisor and
participate in global functional initiatives as appropriate.Minimum
Requirements/Qualifications:
- Bachelor's degree in Materials Sciences, Chemical Engineering,
Mechanical Engineering with 5+ years relevant industry experience
in process safety, manufacturing; chemical or pharmaceutical
industry preferred.
- Master's degree in Materials Sciences, Chemical Engineering,
Mechanical Engineering with 3+ years relevant industry experience
in process safety, manufacturing; chemical or pharmaceutical
industry preferred.
- Previous experience working in a lab setting.
- Previous experience working in a pilot plant setting a
plus.
- Previous experience in process safety in the pharmaceutical,
agrochemical, fine chemical or related industry preferred.
- Previous experience with HAZOPs and/or PHAs preferred.
- Experience using relevant process safety equipment (e.g. DSC,
RC1, EasymaxHFCal, ARC, Tsu) preferred.
- Previous experience with software packages for process safety
prediction (e.g., AKTS, Aspen Plus, gPROMS) a plus, focusing on the
prediction of thermal, chemical, and kinetic properties.
- Understanding of FAIR data principles (Findable, Accessible,
Interoperable, Reusable) to drive efficient data management for
safety modeling and analytics.Knowledge and Skills:
- Analytical and Problem-Solving Skills - Able to troubleshoot
critical issues or problems and determine causes and possible
solutions using appropriate information.
- Teamwork - Ability to work well in a highly cross-functional
team environment.
- Communication - Able to express oneself clearly and concisely
within team; documents issues and/or concerns concisely with
colleagues; timely and effectively communicates issues to
supervisor; technical writing skills to support contributing to
internal technical documents.
- Organization - Exercises good time management and
prioritization skills and is able to successfully manage multiple
tasks simultaneously.
- Knowledge Sharing - Ability to capture organizational
knowledge; improve solutions, processes, and deliverables through
use of information; improve information capital by contributing
experience, theories, deliverables, and models for others to
use.
- Technical - Advanced proficiency in use of applicable lab
equipment and operations.More about us:At Takeda, we are
transforming patient care through the development of novel
specialty pharmaceuticals and best in class patient support
programs. Takeda is a patient-focused company that will inspire and
empower you to grow through life-changing work.Certified as a
Global Top Employer, Takeda offers stimulating careers, encourages
innovation, and strives for excellence in everything we do. We
foster an inclusive, collaborative workplace, in which our teams
are united by an unwavering commitment to deliver Better Health and
a Brighter Future to people around the world.#LI-SB1Takeda
Compensation and Benefits SummaryWe understand compensation is an
important factor as you consider the next step in your career. We
are committed to equitable pay for all employees, and we strive to
be more transparent with our pay practices.For Location: Boston,
MAU.S. Base Salary Range: $96,600.00 - $151,800.00The estimated
salary range reflects an anticipated range for this position. The
actual base salary offered may depend on a variety of factors,
including the qualifications of the individual applicant for the
position, years of relevant experience, specific and unique skills,
level of education attained, certifications or other professional
licenses held, and the location in which the applicant lives and/or
from which they will be performing the job. The actual base salary
offered will be in accordance with state or local minimum wage
requirements for the job location.U.S. based employees may be
eligible for short-term and/or long-term incentives. U.S. based
employees may be eligible to participate in medical, dental, vision
insurance, a 401(k) plan and company match, short-term and
long-term disability coverage, basic life insurance, a tuition
reimbursement program, paid volunteer time off, company holidays,
and well-being benefits, among others. U.S. based employees are
also eligible to receive, per calendar year, up to 80 hours of sick
time, and new hires are eligible to accrue up to 120 hours of paid
vacation.EEO StatementTakeda is proud in its commitment to creating
a diverse workforce and providing equal employment opportunities to
all employees and applicants for employment without regard to race,
color, religion, sex, sexual orientation, gender identity, gender
expression, parental status, national origin, age, disability,
citizenship status, genetic information or characteristics, marital
status, status as a Vietnam era veteran, special disabled veteran,
or other protected veteran in accordance with applicable federal,
state and local laws, and any other characteristic protected by
law.LocationsBoston, MAWorker TypeEmployeeWorker
Sub-TypeRegularTime TypeFull time
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Keywords: Takeda, Taunton , Engineer IV, Process Safety, Engineering , Boston, Massachusetts
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